BIOPEP-UWM: Report

ID 5365
Name Cecropin B
sequence
GWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATARG
Function:
Cecropins have lytic and antibacterial activity against several gram-positive and gram-negative bacteria.
 
Number of residues
40
Activity code
ab
Activity :
antibacterial
Chemical mass 4283.8848 Monoisotopic mass 4281.3976
EC50 :
0.00 µM


Bibliographic data:
Authors
Kylsten P., Samakovlis C., Hultmark D.;
Title
"The cecropin locus in Drosophila; a compact gene cluster involved in the response to infection.";EMBO J. 9:217-224.
Year Source
1990 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(O)[C@]([H])(NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@]([H])(CCC(N)=O)NC(=O)CNC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CCCCN)NC(=O)CNC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@]([H])(C)CC)[C@@]([H])(C)CC)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CO)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@]([H])(C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(O)=O)[C@@]([H])(C)O)[C@@]([H])(C)CC)[C@@]([H])(C)CC

InChI=1S/C186H317N63O53/c1-28-91(15)142(245-167(287)114(52-43-69-208-186(202)203)229-165(285)119(57-62-137(262)263)234-179(299)144(93(17)30-3)246-166(286)111(48-36-39-65-189)228-159(279)109(46-34-37-63-187)222-134(259)80-210-156(276)120(70-86(5)6)236-161(281)110(47-35-38-64-188)227-160(280)112(50-41-67-206-184(198)199)230-170(290)122(72-88(9)10)237-171(291)123(224-133(258)77-190)73-104-78-209-107-45-33-32-44-106(104)107)175(295)212-81-135(260)223-115(53-58-128(191)253)163(283)238-124(74-105-79-204-85-214-105)172(292)249-147(103(27)252)182(302)232-113(51-42-68-207-185(200)201)162(282)239-126(76-138(264)265)169(289)218-98(22)153(273)241-127(84-250)174(294)247-145(94(18)31-4)180(300)233-118(56-61-131(194)256)168(288)243-141(90(13)14)177(297)240-121(71-87(7)8)157(277)211-82-136(261)242-143(92(16)29-2)178(298)220-99(23)151(271)226-117(55-60-130(193)255)164(284)231-116(54-59-129(192)254)158(278)217-95(19)148(268)215-97(21)152(272)235-125(75-132(195)257)173(293)244-140(89(11)12)176(296)219-96(20)149(269)216-101(25)154(274)248-146(102(26)251)181(301)221-100(24)150(270)225-108(49-40-66-205-183(196)197)155(275)213-83-139(266)267/h32-33,44-45,78-79,85-103,108-127,140-147,209,250-252H,28-31,34-43,46-77,80-84,187-190H2,1-27H3,(H2,191,253)(H2,192,254)(H2,193,255)(H2,194,256)(H2,195,257)(H,204,214)(H,210,276)(H,211,277)(H,212,295)(H,213,275)(H,215,268)(H,216,269)(H,217,278)(H,218,289)(H,219,296)(H,220,298)(H,221,301)(H,222,259)(H,223,260)(H,224,258)(H,225,270)(H,226,271)(H,227,280)(H,228,279)(H,229,285)(H,230,290)(H,231,284)(H,232,302)(H,233,300)(H,234,299)(H,235,272)(H,236,281)(H,237,291)(H,238,283)(H,239,282)(H,240,297)(H,241,273)(H,242,261)(H,243,288)(H,244,293)(H,245,287)(H,246,286)(H,247,294)(H,248,274)(H,249,292)(H,262,263)(H,264,265)(H,266,267)(H4,196,197,205)(H4,198,199,206)(H4,200,201,207)(H4,202,203,208)/t91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102+,103+,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,140-,141-,142-,143-,144-,145-,146-,147-/m0/s1

InChIKey=PROJMNHQIJJWOS-ALIVBTJYSA-N


Database reference:
SWISS-PROT ENTRY OF PREPROPEPTIDE CECB_DROME