BIOPEP-UWM: Report

ID 5366
Name cecropin B
sequence
KWKIFKKIEKVGRNIRNGIIKAGPAVAVLGEAKALG
Function:
Cecropins have lytic and antibacterial activity against several gram-positive and gram-negative bacteria.
 
Number of residues
36
Activity code
ab
Activity :
antibacterial
Chemical mass 3874.6553 Monoisotopic mass 3872.3287
EC50 :
0.00 µM


Bibliographic data:
Authors
Qu X.-M., Steiner H., Engstroem A., Bennich H., Boman H.G.;
Title
"Insect immunity: isolation and structure of cecropins B and D from pupae of the Chinese oak silk moth, Antheraea pernyi."; Eur. J. Biochem. 127:219-224.
Year Source
1982 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(N)=O)C(=O)NCC(=O)N[C@]([H])(C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(O)=O)[C@@]([H])(C)CC)[C@@]([H])(C)CC)[C@@]([H])(C)CC)[C@@]([H])(C)CC)[C@@]([H])(C)CC

InChI=1S/C179H306N52O43/c1-26-98(16)142(177(274)230-146(102(20)30-5)175(272)214-115(59-38-45-73-182)157(254)202-103(21)147(244)200-91-135(237)231-80-52-66-129(231)169(266)205-106(24)150(247)224-140(96(12)13)171(268)206-107(25)151(248)225-141(97(14)15)172(269)221-124(82-94(8)9)153(250)197-88-132(234)208-121(67-69-136(238)239)158(255)204-104(22)148(245)209-114(58-37-44-72-181)156(253)203-105(23)149(246)217-123(81-93(6)7)154(251)201-92-138(242)243)223-134(236)90-198-155(252)127(85-130(188)232)219-161(258)120(65-51-79-195-179(192)193)215-173(270)144(100(18)28-3)229-168(265)128(86-131(189)233)220-159(256)113(64-50-78-194-178(190)191)207-133(235)89-199-170(267)139(95(10)11)226-163(260)117(61-40-47-75-184)211-162(259)122(68-70-137(240)241)216-174(271)143(99(17)27-2)227-164(261)118(62-41-48-76-185)210-160(257)116(60-39-46-74-183)212-166(263)125(83-108-53-32-31-33-54-108)222-176(273)145(101(19)29-4)228-165(262)119(63-42-49-77-186)213-167(264)126(218-152(249)111(187)56-36-43-71-180)84-109-87-196-112-57-35-34-55-110(109)112/h31-35,53-55,57,87,93-107,111,113-129,139-146,196H,26-30,36-52,56,58-86,88-92,180-187H2,1-25H3,(H2,188,232)(H2,189,233)(H,197,250)(H,198,252)(H,199,267)(H,200,244)(H,201,251)(H,202,254)(H,203,253)(H,204,255)(H,205,266)(H,206,268)(H,207,235)(H,208,234)(H,209,245)(H,210,257)(H,211,259)(H,212,263)(H,213,264)(H,214,272)(H,215,270)(H,216,271)(H,217,246)(H,218,249)(H,219,258)(H,220,256)(H,221,269)(H,222,273)(H,223,236)(H,224,247)(H,225,248)(H,226,260)(H,227,261)(H,228,262)(H,229,265)(H,230,274)(H,238,239)(H,240,241)(H,242,243)(H4,190,191,194)(H4,192,193,195)/t98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,111-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,139-,140-,141-,142-,143-,144-,145-,146-/m0/s1

InChIKey=FOKWEPZSTZBMKH-JXYRABFOSA-N


Database reference:
SWISS-PROT ENTRY OF PREPROPEPTIDE: CECB_ANTPE