BIOPEP-UWM: Report

ID 5376
Name gaegurin 4
sequence
GILDTLKQFAKGVGKDLVKGAAQGVLSTVSCKLAKTC
Function:
Has a non-hemolytic activity. Has a broad spectrum of activity against both gram-positive and gram-negative bacteria, fungi and protozoa.
 
Number of residues
37
Activity code
ab
Activity :
antibacterial
Chemical mass 3749.4371 Monoisotopic mass 3747.0724
EC50 :
0.00 µM


Bibliographic data:
Authors
Park J.M., Jung J.-E., Lee B.J.;
Title
"Antimicrobial peptides from the skin of a Korean frog, Rana rugosa."; Biochem. Biophys. Res. Commun. 205:948-954.
Year Source
1994 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CS)C(=O)O

InChI=1/C165H287N45O49S2/c1-28-88(20)130(203-119(218)70-172)161(254)197-107(64-81(6)7)149(242)195-112(69-125(225)226)153(246)209-131(93(25)213)162(255)198-106(63-80(4)5)148(241)187-100(49-35-41-59-169)142(235)189-104(53-55-118(174)217)144(237)193-110(67-96-44-30-29-31-45-96)147(240)182-91(23)136(229)184-97(46-32-38-56-166)138(231)176-73-122(221)204-126(84(12)13)157(250)178-72-121(220)183-99(48-34-40-58-168)141(234)194-111(68-124(223)224)151(244)192-109(66-83(10)11)152(245)206-128(86(16)17)159(252)190-98(47-33-39-57-167)139(232)175-71-120(219)179-89(21)134(227)180-90(22)135(228)186-103(52-54-117(173)216)140(233)177-74-123(222)205-127(85(14)15)158(251)196-108(65-82(8)9)150(243)199-114(76-212)155(248)210-133(95(27)215)164(257)207-129(87(18)19)160(253)200-113(75-211)154(247)201-115(77-260)156(249)188-101(50-36-42-60-170)143(236)191-105(62-79(2)3)146(239)181-92(24)137(230)185-102(51-37-43-61-171)145(238)208-132(94(26)214)163(256)202-116(78-261)165(258)259/h29-31,44-45,79-95,97-116,126-133,211-215,260-261H,28,32-43,46-78,166-172H2,1-27H3,(H2,173,216)(H2,174,217)(H,175,232)(H,176,231)(H,177,233)(H,178,250)(H,179,219)(H,180,227)(H,181,239)(H,182,240)(H,183,220)(H,184,229)(H,185,230)(H,186,228)(H,187,241)(H,188,249)(H,189,235)(H,190,252)(H,191,236)(H,192,244)(H,193,237)(H,194,234)(H,195,242)(H,196,251)(H,197,254)(H,198,255)(H,199,243)(H,200,253)(H,201,247)(H,202,256)(H,203,218)(H,204,221)(H,205,222)(H,206,245)(H,207,257)(H,208,238)(H,209,246)(H,210,248)(H,223,224)(H,225,226)(H,258,259)/t88-,89-,90-,91-,92-,93+,94+,95+,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,126-,127-,128-,129-,130-,131-,132-,133-/s2

InChIKey=NRTGWFHHCOAFJU-QVZWMMGNNA-N


Database reference:
SWISS-PROT GAE4_RANRU