BIOPEP-UWM: Report

ID 5378
Name gaegurin 6
sequence
FLPLLAGLAANFLPTIICKISYKC
Function:
Has a non-hemolytic activity. Has a broad spectrum of activity against both gram-positive and gram-negative bacteria, fungi and protozoa.
 
Number of residues
24
Activity code
ab
Activity :
antibacterial
Chemical mass 2610.2211 Monoisotopic mass 2608.4478
EC50 :
0.00 µM


Bibliographic data:
Authors
Park J.M., Jung J.-E., Lee B.J.;
Title
"Antimicrobial peptides from the skin of a Korean frog, Rana rugosa."; Biochem. Biophys. Res. Commun. 205:948-954.
Year Source
1994 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS)C(=O)O

InChI=1/C125H201N27O29S2/c1-21-70(14)99(119(174)144-92(62-153)115(170)140-88(59-79-44-46-80(155)47-45-79)112(167)135-82(40-30-32-48-126)107(162)146-94(64-183)125(180)181)147-108(163)83(41-31-33-49-127)136-116(171)93(63-182)145-120(175)100(71(15)22-2)148-121(176)101(72(16)23-3)149-122(177)102(76(20)154)150-118(173)96-43-35-51-152(96)124(179)91(56-69(12)13)143-113(168)87(58-78-38-28-25-29-39-78)139-114(169)89(60-97(129)156)137-105(160)75(19)131-104(159)74(18)133-109(164)84(52-65(4)5)134-98(157)61-130-103(158)73(17)132-110(165)85(53-66(6)7)138-111(166)86(54-67(8)9)141-117(172)95-42-34-50-151(95)123(178)90(55-68(10)11)142-106(161)81(128)57-77-36-26-24-27-37-77/h24-29,36-39,44-47,65-76,81-96,99-102,153-155,182-183H,21-23,30-35,40-43,48-64,126-128H2,1-20H3,(H2,129,156)(H,130,158)(H,131,159)(H,132,165)(H,133,164)(H,134,157)(H,135,167)(H,136,171)(H,137,160)(H,138,166)(H,139,169)(H,140,170)(H,141,172)(H,142,161)(H,143,168)(H,144,174)(H,145,175)(H,146,162)(H,147,163)(H,148,176)(H,149,177)(H,150,173)(H,180,181)/t70-,71-,72-,73-,74-,75-,76+,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,99-,100-,101-,102-/s2

InChIKey=CRJBXHVDYXVALU-TYBHGMCLNA-N

From Rana rugosa (Wrinkled frog).
Disulfid: 18-24


Database reference:
SWISS-PROT GAE6_RANRU