BIOPEP-UWM: Report

ID 5389
Name dermaseptin B1
sequence
AMWKDVLKKIGTVALHAGKAALGAVADTISQG

Function:
Possesses a potent antimicrobial activity against gram-positive and gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure
 
Number of residues
32
Activity code
ab
Activity :
antibacterial
Chemical mass 3221.7621 Monoisotopic mass 3219.7746
EC50 :
0.00 µM



Bibliographic data:
Authors
Amiche M., Ducancel F., Mor A., Boulain J.C., Menez A., Nicolas P.;
Title
Precursors of vertebrate peptide antibiotics dermaseptin b and adenoregulin have extensive sequence identities with precursors of opioid peptides dermorphin, dermenkephalin, and deltorphins.";J.Biol. Chem. 269:17847-17852.
Year Source
1994 Journal



Additional information:
from Phyllomedusa bicolor (Two-colored leaf frog)
Amidated C-terminus.



Database reference: