BIOPEP-UWM: Report

ID 5391
Name ranalexin
sequence
FLGGLIKIVPAMICAVTKKC
Function:
Potent microbicidal activity, active against s.aureus and e.coli. It acts as well as a membrane-disruptive agent at higher concentrations.
 
Number of residues
20
Activity code
ab
Activity :
antibacterial
Chemical mass 2105.7122 Monoisotopic mass 2104.1936
EC50 :
0.00 µM


Bibliographic data:
Authors
Vignal E., Chavanieu A., Roch P., Chiche L., Grassy G., Calas B., Aumelas A.;
Title
"Solution structure of the antimicrobial peptide ranalexin and a study of its interaction with perdeuterated dodecylphosphocholine micelles."; Eur. J. Biochem. 253:221-228.
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS)C(=O)O



InChI=1S/C97H169N23O22S3/c1-19-55(12)76(118-88(132)68(45-52(6)7)106-73(123)48-102-72(122)47-103-83(127)67(44-51(4)5)111-82(126)62(101)46-61-32-23-22-24-33-61)92(136)109-65(36-27-30-41-100)86(130)117-78(57(14)21-3)94(138)115-75(54(10)11)96(140)120-42-31-37-71(120)90(134)105-58(15)80(124)107-66(38-43-145-18)87(131)116-77(56(13)20-2)93(137)112-69(49-143)89(133)104-59(16)81(125)114-74(53(8)9)91(135)119-79(60(17)121)95(139)110-64(35-26-29-40-99)84(128)108-63(34-25-28-39-98)85(129)113-70(50-144)97(141)142/h22-24,32-33,51-60,62-71,74-79,121,143-144H,19-21,25-31,34-50,98-101H2,1-18H3,(H,102,122)(H,103,127)(H,104,133)(H,105,134)(H,106,123)(H,107,124)(H,108,128)(H,109,136)(H,110,139)(H,111,126)(H,112,137)(H,113,129)(H,114,125)(H,115,138)(H,116,131)(H,117,130)(H,118,132)(H,119,135)(H,141,142)/t55-,56-,57-,58-,59-,60+,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,74-,75-,76-,77-,78-,79-/m0/s1


InChIKey: KWUAGMXKVPEYRD-KCXFZFQESA-N


From Rana catesbeiana (Bull frog).
Disulfid: 14-20


Database reference:
SWISS-PROT RLXN_RANCA