BIOPEP-UWM: Report

ID 5394
Name rugosin C
sequence
GILDSFKQFAKGVGKDLIKGAAQGVLSTMSCKLAKTC
Function:
SHOWS ANTIBACTERIAL ACTIVITY AGAINST GRAM-POSITIVE BACTERIA
 
Number of residues
37
Activity code
ab
Activity :
antibacterial
Chemical mass 3815.5195 Monoisotopic mass 3813.0289
EC50 :
0.00 µM


Bibliographic data:
Authors
Suzuki S., Ohe Y., Kagegawa T., Tatemoto K.;
Title
Isolation and characterization of novel antimicrobial peptides, rugosins A, B and C, from the skin of the frog, Rana rugosa."; Biochem. Biophys. Res. Commun. 212:249-254(1995).
Year Source
1995 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CS)C(=O)O


InChI=1S/C168H285N45O49S3/c1-24-90(15)133(208-124(221)74-175)164(257)202-110(67-85(5)6)152(245)200-116(73-130(228)229)156(249)204-117(79-214)158(251)198-114(71-99-46-30-27-31-47-99)154(247)190-103(51-35-41-62-172)145(238)192-107(55-57-123(177)220)147(240)197-113(70-98-44-28-26-29-45-98)151(244)185-94(19)139(232)187-100(48-32-38-59-169)141(234)179-77-127(224)209-131(88(11)12)162(255)181-76-126(223)186-102(50-34-40-61-171)144(237)199-115(72-129(226)227)155(248)196-112(69-87(9)10)157(250)211-134(91(16)25-2)165(258)193-101(49-33-39-60-170)142(235)178-75-125(222)182-92(17)137(230)183-93(18)138(231)189-106(54-56-122(176)219)143(236)180-78-128(225)210-132(89(13)14)163(256)201-111(68-86(7)8)153(246)205-119(81-216)160(253)213-135(96(21)217)166(259)194-108(58-65-265-23)148(241)203-118(80-215)159(252)206-120(82-263)161(254)191-104(52-36-42-63-173)146(239)195-109(66-84(3)4)150(243)184-95(20)140(233)188-105(53-37-43-64-174)149(242)212-136(97(22)218)167(260)207-121(83-264)168(261)262/h26-31,44-47,84-97,100-121,131-136,214-218,263-264H,24-25,32-43,48-83,169-175H2,1-23H3,(H2,176,219)(H2,177,220)(H,178,235)(H,179,234)(H,180,236)(H,181,255)(H,182,222)(H,183,230)(H,184,243)(H,185,244)(H,186,223)(H,187,232)(H,188,233)(H,189,231)(H,190,247)(H,191,254)(H,192,238)(H,193,258)(H,194,259)(H,195,239)(H,196,248)(H,197,240)(H,198,251)(H,199,237)(H,200,245)(H,201,256)(H,202,257)(H,203,241)(H,204,249)(H,205,246)(H,206,252)(H,207,260)(H,208,221)(H,209,224)(H,210,225)(H,211,250)(H,212,242)(H,213,253)(H,226,227)(H,228,229)(H,261,262)/t90-,91-,92-,93-,94-,95-,96+,97+,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,131-,132-,133-,134-,135-,136-/m0/s1


InChIKey: UBBGGWXUZQARIH-GWNDQINQSA-N

from Rana rugosa (Wrinkled frog)
disulfid 31-37

SWISS-PROT RUGC_RANRU


Database reference: