BIOPEP-UWM: Report

ID 5395
Name gaegurin 1
sequence
SLFSLIKAGAKFLGKNLLKQGACYAACKASKQC
Function:
Has a broad spectrum of activity against both gram-positive and gram-negative bacteria, fungi and protozoa.
 
Number of residues
33
Activity code
ab
Activity :
antibacterial
Chemical mass 3462.1518 Monoisotopic mass 3459.8498
EC50 :
0.00 µM


Bibliographic data:
Authors
Park J.M., Jung J.-E., Lee B.J.;
Title
"Antimicrobial peptides from the skin of a Korean frog, Rana rugosa."; Biochem. Biophys. Res. Commun. 205:948-954.
Year Source
1994 Journal


Additional information:
Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CS)C(=O)O


InChI=1S/C155H258N42O41S3/c1-19-85(12)125(197-149(231)109(66-84(10)11)187-151(233)115(76-200)193-147(229)112(68-93-40-24-21-25-41-93)189-144(226)106(63-81(4)5)183-132(214)96(162)74-198)154(236)182-99(44-28-34-58-158)136(218)172-86(13)126(208)166-71-122(205)169-87(14)128(210)176-100(45-29-35-59-159)140(222)188-111(67-92-38-22-20-23-39-92)146(228)184-105(62-80(2)3)134(216)168-73-124(207)175-97(42-26-32-56-156)137(219)191-113(70-121(165)204)148(230)186-108(65-83(8)9)145(227)185-107(64-82(6)7)143(225)177-101(46-30-36-60-160)138(220)180-103(52-54-119(163)202)133(215)167-72-123(206)170-88(15)129(211)194-117(78-240)153(235)190-110(69-94-48-50-95(201)51-49-94)142(224)174-89(16)127(209)171-90(17)131(213)195-116(77-239)152(234)179-98(43-27-33-57-157)135(217)173-91(18)130(212)192-114(75-199)150(232)178-102(47-31-37-61-161)139(221)181-104(53-55-120(164)203)141(223)196-118(79-241)155(237)238/h20-25,38-41,48-51,80-91,96-118,125,198-201,239-241H,19,26-37,42-47,52-79,156-162H2,1-18H3,(H2,163,202)(H2,164,203)(H2,165,204)(H,166,208)(H,167,215)(H,168,216)(H,169,205)(H,170,206)(H,171,209)(H,172,218)(H,173,217)(H,174,224)(H,175,207)(H,176,210)(H,177,225)(H,178,232)(H,179,234)(H,180,220)(H,181,221)(H,182,236)(H,183,214)(H,184,228)(H,185,227)(H,186,230)(H,187,233)(H,188,222)(H,189,226)(H,190,235)(H,191,219)(H,192,212)(H,193,229)(H,194,211)(H,195,213)(H,196,223)(H,197,231)(H,237,238)/t85-,86-,87-,88-,89-,90-,91-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,125-/m0/s1


InChIKey: JFRKHNPYYNDSGD-YUXNIHIASA-N



From Rana rugosa (Wrinkled frog).
Disulfid: 27-33


Database reference:
SWISS-PROT GAE1_RANRU