BIOPEP-UWM: Report

ID 5457
Name aurein 2.1.1
sequence
LDIVKKVVGAFGSLG

Function:
Antimicrobial activity against L.lactis, M.luteus, P.multocida, S.aureus, S.epidermidis and S.uberis. Probably acts by disturbing membrane functions with its amphipathic structure. Shows anticancer activity.
 
Number of residues
15
Activity code
ab
Activity :
antibacterial
Chemical mass 1502.7916 Monoisotopic mass 1501.8840
EC50 :
0.00 µM



Bibliographic data:
Authors
Rozek T., Wegener K.L., Bowie J.H., Olver I.N., Carver J.A., Wallace J.C., Tyler M.J.;
Title
"The antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2."; Eur. J. Biochem. 267:5330-5341.
Year Source
2000 Journal



Additional information:
From Litoria raniformis (Southern bell frog), Litoria aurea (Green and golden bell frog).
Amidated C-terminus.



Database reference:
SWISS-PROT AU21_LITRA