BIOPEP-UWM: Report

ID 5459
Name Antifungal peptide
sequence
FKCRRWQWRW
Function:
Antimicrobial activity against L.lactis, M.luteus, P.multocida, S.aureus, S.epidermidis and S.uberis. Probably acts by disturbing membrane functions with its amphipathic structure. Shows anticancer activity.
 
Number of residues
10
Activity code
af
Activity :
antifungal
Chemical mass 1551.8173 Monoisotopic mass 1550.7809
EC50 :
0.00 µM


Bibliographic data:
Authors
Ueta E., Tanida T., Osaki T.
Title
A novel bovine lactoferrin peptide, FKCRRWQWRM, suppresses Candida cell growth and activates neutrophils. J. Pept. Res., 57, 240-249, 2001
Year Source
2001 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C74H102N24O12S/c75-29-11-10-23-52(90-62(100)48(76)33-41-15-2-1-3-16-41)66(104)98-60(40-111)70(108)93-53(24-12-30-84-72(78)79)63(101)91-54(25-13-31-85-73(80)81)64(102)95-58(35-43-38-88-50-21-8-5-18-46(43)50)69(107)94-56(27-28-61(77)99)67(105)96-57(34-42-37-87-49-20-7-4-17-45(42)49)68(106)92-55(26-14-32-86-74(82)83)65(103)97-59(71(109)110)36-44-39-89-51-22-9-6-19-47(44)51/h1-9,15-22,37-39,48,52-60,87-89,111H,10-14,23-36,40,75-76H2,(H2,77,99)(H,90,100)(H,91,101)(H,92,106)(H,93,108)(H,94,107)(H,95,102)(H,96,105)(H,97,103)(H,98,104)(H,109,110)(H4,78,79,84)(H4,80,81,85)(H4,82,83,86)/t48-,52-,53-,54-,55-,56-,57-,58-,59-,60-/m0/s1

InChIKey=MSJHDOJCHMNYPI-PVXHDPALSA-N


Immunostimulating peptide according to the BIOPEP-UWM database of bioactive peptides (ID 5297)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 5297