BIOPEP-UWM: Report

ID 5487
Name ceratotoxin D
sequence
SIGTAVKKAVPIAKKVGKVAIPIAKAVLSVVGQLVG
Function:
Female-specific peptides with potent activity against gram-positive and gram-negative bacteria. They have as well hemolytic activity. These proteins are stable even at 100 degrees celsius.
 
Number of residues
36
Activity code
ab
Activity :
antibacterial
Chemical mass 3511.3223 Monoisotopic mass 3509.2096
EC50 :
0.00 µM


Bibliographic data:
Authors
Rosetto M., de Filippis T., Manetti A.G.O., Marchini D., Baldari C.T., Dallai R.;
Title
"The genes encoding the antibacterial sex-specific peptides ceratotoxins are clustered in the genome of the medfly Ceratitis capitata."; Insect Biochem. Mol. Biol. 27:1039-1046.
Year Source
1997 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)NCC(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)O


InChI=1S/C163H293N43O41/c1-36-90(25)127(201-138(222)101(170)78-207)154(238)174-76-117(213)192-131(100(35)209)161(245)181-98(33)135(219)193-123(86(17)18)156(240)188-106(58-44-50-68-168)142(226)186-104(56-42-48-66-166)140(224)177-97(32)136(220)200-126(89(23)24)162(246)205-70-52-60-112(205)149(233)202-128(91(26)37-2)159(243)180-95(30)133(217)185-105(57-43-49-67-167)141(225)187-107(59-45-51-69-169)145(229)195-119(82(9)10)151(235)172-74-115(211)182-102(54-40-46-64-164)144(228)197-122(85(15)16)155(239)178-99(34)137(221)204-130(93(28)39-4)163(247)206-71-53-61-113(206)150(234)203-129(92(27)38-3)160(244)179-94(29)132(216)184-103(55-41-47-65-165)139(223)176-96(31)134(218)194-124(87(19)20)157(241)190-109(72-80(5)6)146(230)191-111(79-208)148(232)198-125(88(21)22)158(242)199-121(84(13)14)152(236)173-75-116(212)183-108(62-63-114(171)210)143(227)189-110(73-81(7)8)147(231)196-120(83(11)12)153(237)175-77-118(214)215/h80-113,119-131,207-209H,36-79,164-170H2,1-35H3,(H2,171,210)(H,172,235)(H,173,236)(H,174,238)(H,175,237)(H,176,223)(H,177,224)(H,178,239)(H,179,244)(H,180,243)(H,181,245)(H,182,211)(H,183,212)(H,184,216)(H,185,217)(H,186,226)(H,187,225)(H,188,240)(H,189,227)(H,190,241)(H,191,230)(H,192,213)(H,193,219)(H,194,218)(H,195,229)(H,196,231)(H,197,228)(H,198,232)(H,199,242)(H,200,220)(H,201,222)(H,202,233)(H,203,234)(H,204,221)(H,214,215)/t90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100+,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-/m0/s1


InChIKey: OVCWLGIRBCPLFF-QJVVZSHOSA-N


From Ceratitis capitata (Mediterranean fruit fly).


Database reference:
SWISS-PROT CERD_CERCA