BIOPEP-UWM: Report

ID 5490
Name styelin C
sequence
GWFGKAFRSVSNFYKKHKTYIHAGLSAATLLGDMTDEEFQEFMQDIEQAREEELLSRQ
Function:
Bactericidal against several gram-positive and gram-negative bacteria.
 
Number of residues
58
Activity code
ab
Activity :
antibacterial
Chemical mass 6786.4715 Monoisotopic mass 6782.2856
EC50 :
0.00 µM


Bibliographic data:
Authors
Zhao C., Liaw L., Lee I.H., Lehrer R.I.;
Title
"cDNA cloning of three cecropin-like antimicrobial peptides (Styelins) from the tunicate, Styela clava."; FEBS Lett. 412:144-148.
Year Source
1997 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: NCC(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O


InChI=1S/C303H457N81O93S2/c1-27-155(15)242(295(471)357-195(94-105-237(415)416)265(441)346-186(84-95-222(309)394)255(431)334-159(19)249(425)340-183(73-54-112-322-301(314)315)257(433)348-189(88-99-231(403)404)262(438)349-190(89-100-232(405)406)263(439)351-192(91-102-234(409)410)267(443)361-201(119-151(7)8)275(451)362-202(120-152(9)10)277(453)377-219(144-386)291(467)345-184(74-55-113-323-302(316)317)258(434)358-198(300(476)477)87-98-225(312)397)381-289(465)217(135-240(421)422)370-266(442)188(86-97-224(311)396)347-270(446)196(106-115-478-25)355-281(457)207(125-168-63-40-32-41-64-168)365-268(444)193(92-103-235(411)412)350-261(437)187(85-96-223(310)395)353-280(456)206(124-167-61-38-31-39-62-167)364-269(445)194(93-104-236(413)414)352-264(440)191(90-101-233(407)408)354-287(463)216(134-239(419)420)374-299(475)246(164(24)391)384-272(448)197(107-116-479-26)356-286(462)215(133-238(417)418)339-230(402)142-327-252(428)199(117-149(3)4)360-276(452)203(121-153(11)12)371-297(473)244(162(22)389)382-251(427)161(21)331-248(424)158(18)335-290(466)218(143-385)376-274(450)200(118-150(5)6)338-229(401)140-326-247(423)157(17)332-273(449)212(130-173-138-320-147-329-173)373-296(472)243(156(16)28-2)380-288(464)210(128-171-78-82-176(393)83-79-171)372-298(474)245(163(23)390)383-271(447)182(72-49-53-111-307)343-284(460)213(131-174-139-321-148-330-174)368-259(435)181(71-48-52-110-306)341-256(432)180(70-47-51-109-305)342-279(455)209(127-170-76-80-175(392)81-77-170)366-282(458)208(126-169-65-42-33-43-66-169)367-285(461)214(132-226(313)398)369-292(468)220(145-387)378-294(470)241(154(13)14)379-293(469)221(146-388)375-260(436)185(75-56-114-324-303(318)319)344-278(454)205(123-166-59-36-30-37-60-166)359-250(426)160(20)333-254(430)179(69-46-50-108-304)336-228(400)141-328-253(429)204(122-165-57-34-29-35-58-165)363-283(459)211(337-227(399)136-308)129-172-137-325-178-68-45-44-67-177(172)178/h29-45,57-68,76-83,137-139,147-164,179-221,241-246,325,385-393H,27-28,46-56,69-75,84-136,140-146,304-308H2,1-26H3,(H2,309,394)(H2,310,395)(H2,311,396)(H2,312,397)(H2,313,398)(H,320,329)(H,321,330)(H,326,423)(H,327,428)(H,328,429)(H,331,424)(H,332,449)(H,333,430)(H,334,431)(H,335,466)(H,336,400)(H,337,399)(H,338,401)(H,339,402)(H,340,425)(H,341,432)(H,342,455)(H,343,460)(H,344,454)(H,345,467)(H,346,441)(H,347,446)(H,348,433)(H,349,438)(H,350,437)(H,351,439)(H,352,440)(H,353,456)(H,354,463)(H,355,457)(H,356,462)(H,357,471)(H,358,434)(H,359,426)(H,360,452)(H,361,443)(H,362,451)(H,363,459)(H,364,445)(H,365,444)(H,366,458)(H,367,461)(H,368,435)(H,369,468)(H,370,442)(H,371,473)(H,372,474)(H,373,472)(H,374,475)(H,375,436)(H,376,450)(H,377,453)(H,378,470)(H,379,469)(H,380,464)(H,381,465)(H,382,427)(H,383,447)(H,384,448)(H,403,404)(H,405,406)(H,407,408)(H,409,410)(H,411,412)(H,413,414)(H,415,416)(H,417,418)(H,419,420)(H,421,422)(H,476,477)(H4,314,315,322)(H4,316,317,323)(H4,318,319,324)/t155-,156-,157-,158-,159-,160-,161-,162+,163+,164+,179-,180-,181-,182-,183-,184-,185-,186-,187-,188-,189-,190-,191-,192-,193-,194-,195-,196-,197-,198-,199-,200-,201-,202-,203-,204-,205-,206-,207-,208-,209-,210-,211-,212-,213-,214-,215-,216-,217-,218-,219-,220-,221-,241-,242-,243-,244-,245-,246-/m0/s1


InChIKey: LGOQHTPMRXKJDL-MMPGLQSGSA-N


From Styela clava (Sea squirt).


Database reference:
SWISS-PROT STYC_STYCL