BIOPEP-UWM: Report

ID 5500
Name drosomycin
sequence
DCLSGRYKGPCAVWDNETCRRVCKEEGRSSGHCSPSLKCWCEGC

Function:
Possesses antifungal activity and is active against a relatively broad spectrum of filamentous fungi. It inhibits spore germination at high concentrations and at low concentrations delays growth of Hyphae which subsequently exhibit abnormal morphology.
 
Number of residues
44
Activity code
ab
Activity :
antibacterial
Chemical mass 4897.5127 Monoisotopic mass 4894.0773
EC50 :
0.00 µM



Bibliographic data:
Authors
Fehlbaum P., Bulet P., Michaut L., Lagueux M., Broekaert W.F., Hetru C., Hoffmann J.A.;
Title
"Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides."; J. Biol. Chem. 269:33159-33163.
Year Source
1994 Journal



Additional information:
From Drosophila melanogaster (Fruit fly).
DISULFID:2-44, 11-33, 19-39, 23-41.



Database reference:
SWISS-PROT: DMYC_DROME