BIOPEP-UWM: Report

ID 5521
Name Androctonin
sequence
RSVCRQIKICRRRGGCYYKCTNRPY

Function:
Active against both bacteria (gram-positive and gram-negative) and filamentous fungi. Acts on the membrane of the bacterial cells. It destabilize a membrane by modifying its properties.
 
Number of residues
25
Activity code
ab
Activity :
antibacterial
Chemical mass 3080.6383 Monoisotopic mass 3078.5428
EC50 :
0.00 µM



Bibliographic data:
Authors
Hetru C., Letellier L., Oren Z., Hoffmann J.A., Shai Y.;
Title
"Androctonin, a novel antimicrobial peptide from scorpion Androctonus australis: solution structure and molecular dynamics simulations in the presence of a lipid monolayer."; J. Biomol. Struct. Dyn. 17:367-380.
Year Source
1999 Journal



Additional information:
From Androctonus australis hector (Sahara scorpion).
Disulfid: 4-20; 10-16.



Database reference:
SWISS-PROT ANDT_ANDAU