BIOPEP-UWM: Report
| ID | 5525 |
| Name | hepcidin 25 ( LEAP-1) |
| sequence |
| Function: | |||
| Strong antimicrobial activity against E.coli ML35P bacterium, N.cinerea and weaker against S.epidermidis, S.aureus ans group b Streptococcus bacteria. Active against fungus C.albicans. No activity against P.aeruginosa bacterium. | |||
| Number of residues | 25 |
Activity code | ab |
| Activity : | antibacterial |
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| Chemical mass | 2797.4194 | Monoisotopic mass | 2795.0846 | |
| EC50 : | 0.00 µM |
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| Bibliographic data: | |
| Authors | |
| Krause A., Neitz S., Maegert H.J., Schulz A., Forssmann W.G., Schulz-Knappe P., Adermann K.; | |
| Title | |
| LEAP-1, a novel highly disulfide-bonded human peptide exhibits antimicrobial activity."; FEBS Lett. 480:147-150. | |
| Year | Source |
| 2000 | Journal |
| Additional information: |
| From Homo sapiens (Human). Disulfid:7-13;10-23;11-22;14-19. |
| Database reference: |
| SWISS-PROT: HEPC_HUMAN |