BIOPEP-UWM: Report
| ID | 5526 |
| Name | hepcidin 20 (LEAP-1) |
| sequence |
| Function: | |||
| Strong antimicrobial activity against E.coli ML35P bacterium, N.cinerea and weaker against S.epidermidis, S.aureus ans group b Streptococcus bacteria. Active against fungus C.albicans. No activity against P.aeruginosa bacterium. | |||
| Number of residues | 20 |
Activity code | ab |
| Activity : | antibacterial |
|||
| Chemical mass | 2199.8012 | Monoisotopic mass | 2197.8307 | |
| EC50 : | 0.00 µM |
|||
| Bibliographic data: | |
| Authors | |
| Krause A., Neitz S., Maegert H.J., Schulz A., Forssmann W.G., Schulz-Knappe P., Adermann K.; | |
| Title | |
| "LEAP-1, a novel highly disulfide-bonded human peptide exhibits antimicrobial activity."; FEBS Lett. 480:147-150. | |
| Year | Source |
| 2000 | Journal |
| Additional information: |
| Ffrom Homo sapiens (Human. Disulfid:2-8;5-18;6-17;9-14. |
| Database reference: |
| SWISS-PROT HEPC_HUMAN |