BIOPEP-UWM: Report

ID 5551
Name Bactenecin 5 (from goat neutrophils)
sequence
RFRPPIRRPPIRPPFNPPFRPPVRPPFRPPFRPPFRPPIGPFP
Function:
: BINDS TO THE LIPID A MOIETY OF BACTERIAL LIPOPOLYSACCHARIDES (LPS), A GLYCOLIPID PRESENT IN THE OUTER MEMBRANE OF ALL GRAM-NEGATIVE BACTERIA. SHOWS A POTENT ANTIMICROBIAL ACTIVITY AGAINST GRAM-NEGATIVE BACTERIA E.COLI, S.TYPHIMURIUM AND P.AERUGINOSA. LESS ACTIVE AGAINST GRAM-POSITIVE BACTERIA S.AUREUS, L.MONOCYTOGENES AND B.SUBTILIS.
 
Number of residues
43
Activity code
ab
Activity :
antibacterial
Chemical mass 5162.1356 Monoisotopic mass 5158.9327
EC50 :
0.00 µM


Bibliographic data:
Authors
Shamova O., Brogden K.A., Zhao C., Nguyen T., Kokryakov V.N., Lehrer R.I.;
Title
"Purification and properties of proline-rich antimicrobial peptides from sheep and goat leukocytes."; Infect. Immun. 67:4106-4111.
Year Source
1999 Journal


Additional information:
from Capra hircus (Goat)


Database reference:
SWISS-PROT BCT5_CAPHI