BIOPEP-UWM: Report

ID 6989
Name coeliac toxic peptide
sequence
QPYP

Function:
 
Number of residues
4
Activity code
ctox
Activity :
celiac toxic
Chemical mass 503.5468 Monoisotopic mass 503.2372
EC50 :
0.00 µM



Bibliographic data:
Authors
McLachlan A., Cullis P. G., Cornell H. J.
Title
The use of extended amino acid motifs for focussing on toxic peptides in coeliac disease. J. Biochem. Mol. Biol. Biophys, 2002, 6 (5), 319 -324
Year Source
2002 Journal



Additional information:
Coeliac disease is a permanent intolerance to the gluten or storage proteins found in some cereals. According to De Ritis and coworkers, small sequences of amino acids are common to the peptides linked with the toxicity. It has also been suggested that Tyr-containing motif is also associated with toxicity.
Peptide derived from apha-gliadin.



Database reference: