BIOPEP-UWM: Report
| ID | 6990 |
| Name | potential coeliac toxic peptide (extended motif) |
| sequence |
| Function: | |||
| Extended motifs were defined as the peptide sequences containing the toxic motifs. They were extended by means of including neighbouring amino acid residues selected from the alpha-gliadin sequence. | |||
| Number of residues | 14 |
Activity code | ctox |
| Activity : | celiac toxic |
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| Chemical mass | 1604.6721 | Monoisotopic mass | 1603.7566 | |
| EC50 : | 0.00 µM |
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| Bibliographic data: | |
| Authors | |
| McLachlan A., Cullis P. G., Cornell H. J. | |
| Title | |
| The use of extended amino acid motifs for focussing on toxic peptides in coeliac disease. J. Biochem. Mol. Biol. Biophys, 2002, 6 (5), 319 -324 | |
| Year | Source |
| 2002 | Journal |
| Additional information: |
| Coeliac disease is a permanent intolerance to the gluten or storage proteins found in some cereals. According to De Ritis and coworkers, small sequences of amino acids are common to the peptides linked with the toxicity. It has also been suggested that Tyr-containing motif is also associated with toxicity. Peptide derived from apha-gliadin. |
| Database reference: |