BIOPEP-UWM: Report
| ID | 7057 |
| Name | L9-P18, cecropin A-magainin 2 hybrid |
| sequence |
| Function: | |||
| Changing P9 to L9 increases alpha-helicity. Higher alpha-helicity of the peptides is involved in the hemolytic and antitumor activity rather than antibacterial activity. Change L9 to P9 will increase antibacterial activity. Active against: Gram+ & Gram-, mammalian cells, cancer cells | |||
| Number of residues | 18 |
Activity code | ac |
| Activity : | anticancer |
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| Chemical mass | 2316.9505 | Monoisotopic mass | 2315.4719 | |
| EC50 : | 0.00 µM |
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| Bibliographic data: | |
| Authors | |
| Shin SY, Lee SH, Yang ST, Park EJ, Lee DG, Lee MK, Eom SH, Song WK, Kim Y, Hahm KS, Kim JI | |
| Title | |
| Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. J Pept Res 2001 Dec;58(6):504-14, http://aps.unmc.edu/AP/database | |
| Year | Source |
| 2005 | www sites |
| Additional information: |
| database ID: AP00501, http://aps.unmc.edu/AP/database |
| Database reference: |