BIOPEP-UWM: Report

ID 7064
Name coeliac toxic peptide
sequence
QPQPFPQQSEQSQQPFQPQPF

Function:
 
Number of residues
21
Activity code
ctox
Activity :
celiac toxic
Chemical mass 2498.6531 Monoisotopic mass 2497.1625
EC50 :
0.00 µM



Bibliographic data:
Authors
Dewar D., Pereira S. P., Ciclitira P. J.
Title
The pathogenesis of coeliac disease. Int. J. Biochem. Cell Biol., 36, 17-24
Year Source
2004 Journal



Additional information:
Coeliac disease is a permanent intolerance to the gluten or storage proteins found in some cereals. According to De Ritis and coworkers, small sequences of amino acids are common to the peptides linked with the toxicity. It has also been suggested that Tyr-containing motif is also associated with toxicity.
Peptide derived from apha-gliadin.



Database reference: