BIOPEP-UWM: Report

ID 7067
Name coeliac toxic peptide
sequence
PYPQPQLPY

Function:
 
Number of residues
9
Activity code
ctox
Activity :
celiac toxic
Chemical mass 1102.2356 Monoisotopic mass 1101.5477
EC50 :
0.00 µM



Bibliographic data:
Authors
Dewar D., Pereira S. P., Ciclitira P. J.
Title
The pathogenesis of coeliac disease. Int. J. Biochem. Cell Biol., 36, 17-24
Year Source
2004 Journal



Additional information:
Coeliac disease is a permanent intolerance to the gluten or storage proteins found in some cereals. According to De Ritis and coworkers, small sequences of amino acids are common to the peptides linked with the toxicity. It has also been suggested that Tyr-containing motif is also associated with toxicity.
Peptide derived from apha-gliadin.



Database reference: