BIOPEP-UWM: Report

ID 7446
Name coeliac toxic peptide
sequence
FPQTQQPQQLFPQSQ

Function:
Synthesised gluten peptide. Treated by tTG and analyzed by mass spectrometry. Q preceding a P was not deamidated by tTG.Proline plays the crucial role in the deamidation of gluten peptides.
 
Number of residues
15
Activity code
ctox
Activity :
celiac toxic
Chemical mass 1801.9471 Monoisotopic mass 1800.8767
EC50 :
0.00 µM



Bibliographic data:
Authors
Vader L. W., De Ru A., van der Wal Y., Kooy Y. M. C., Benckhuijsen W., Mearin M. L., Drijfhout J. W., Van Veelen P. A., Koning F.
Title
Specificity of tissue transglutaminase explains cereal toxicity in celiac disease. J. Exp. Med., 2002, 195, 5, 643-649
Year Source
2002 Journal



Additional information:



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