BIOPEP-UWM: Report

ID 7469
Name coeliac toxic peptide
sequence
VVKVGGSSSLGW

Function:
Celiac peptide recognized by sera of patients with active disease. Peptide was recognized by serum IgA immunoglobulins with patients with GCD (gluten-containing diet), but not with patients of GFD (gluten-free diet).
 
Number of residues
12
Activity code
ctox
Activity :
celiac toxic
Chemical mass 1175.3307 Monoisotopic mass 1174.6326
EC50 :
0.00 µM



Bibliographic data:
Authors
Zanoni G., Navone R., Lunardi C., Tridente G., Bason C., Sivori S., Beri R., Dolcino M., Corrocher R., Pucetti A.
Title
In celiac disease, a subset of antibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes. PLoS Medicine, 2006, 3, 9, 1637-1653
Year Source
2006 Journal



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