BIOPEP-UWM: Report

ID 7473
Name coeliac toxic peptide
sequence
RIRVGQSMNMGS

Function:
Transglutaminase fragment: 476-487 taken from Swiss-Prot using BLASTP sharing high homology to peptide with BIOPEP ID: 7469. This agent is correlated with the intestinal damage and potentially involved in human pathology of celiac disease.
 
Number of residues
12
Activity code
ctox
Activity :
celiac toxic
Chemical mass 1335.5550 Monoisotopic mass 1334.6527
EC50 :
0.00 µM



Bibliographic data:
Authors
Zanoni G., Navone R., Lunardi C., Tridente G., Bason C., Sivori S., Beri R., Dolcino M., Corrocher R., Pucetti A.
Title
In celiac disease, a subset of antibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes. PLoS Medicine, 2006, 3, 9, 1637-1653
Year Source
2006 Journal



Additional information:



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