BIOPEP-UWM: Report

ID 7494
Name ACE inhibitor (from bovine beta-CN)
sequence
LNVPGEIVE
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
9
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 969.0869 Monoisotopic mass 968.5161
IC50 :
300.00 µM


Bibliographic data:
Authors
Gobbetti M., Ferranti P., Smacchi E., Goffredi F., Addeo F.
Title
Production of angiotensin-I-converting-enzyme-inhibitory peptides in fermented milks started by Lactobacillus delbrueckii subsp. bulgaricus SS1 and Lactococcus lactis subsp. cremoris FT4. Appl. Environ. Microbiol., 66, 3898-3904, 2000
Year Source
2000 dissertation


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C43H72N10O15/c1-9-23(8)35(41(65)50-33(21(4)5)40(64)48-26(43(67)68)13-15-32(58)59)52-37(61)25(12-14-31(56)57)47-30(55)19-46-39(63)28-11-10-16-53(28)42(66)34(22(6)7)51-38(62)27(18-29(45)54)49-36(60)24(44)17-20(2)3/h20-28,33-35H,9-19,44H2,1-8H3,(H2,45,54)(H,46,63)(H,47,55)(H,48,64)(H,49,60)(H,50,65)(H,51,62)(H,52,61)(H,56,57)(H,58,59)(H,67,68)/t23-,24-,25-,26-,27-,28-,33-,34-,35-/m0/s1

InChIKey=UYEBAICRFOUJMF-KFXKGJFASA-N


Database reference:
AHTPDB: ID 2477, 3409, 3648, 5951, 5955, 6504

FeptideDB: ID 7494

MBPDB: Peptide LNVPGEIVE

PubChem: CID 101051701

SATPdb: ID satpdb12900