BIOPEP-UWM: Report

ID 7499
Name Name ACE inhibitor (from bovine alphas1-CN)
sequence
FVAP

Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 432.5120 Monoisotopic mass 432.2365
IC50 :
10.00 µM



Bibliographic data:
Authors
Maruyama S., Nakagomi K., Tomizuka N., Suzuki H.
Title
Angiotensin I-converting enzyme inhibitor derived from an enzymatic hydrolysate of casein. Isolation and bradykinin-potentiating activity on the uterus. Agric. Biol. Chem., 49, 1405-1409 (1985)
Year Source
1985 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N2[C@@H](CCC2)C(=O)O


InChI=1S/C22H32N4O5/c1-13(2)18(25-19(27)16(23)12-15-8-5-4-6-9-15)20(28)24-14(3)21(29)26-11-7-10-17(26)22(30)31/h4-6,8-9,13-14,16-18H,7,10-12,23H2,1-3H3,(H,24,28)(H,25,27)(H,30,31)/t14-,16-,17-,18-/m0/s1

InChIKey=PTCUFGUAPHEYOL-DKIMLUQUSA-N



Database reference:
AHTPDB: ID 2947, 4380, 4888, 5279, 5848, 6509

BindingDB: ID 50348862

BioPepDB: ID biopep00299

ChEMBL: ID CHEMBL1807679

ChemSpider: ID 26618430

EROP-Moscow: ID E14538

FeptideDB: ID 7499

PubChem: CID 56676985

SATPdb: ID satpdb28895

SureChEMBL: ID SCHEMBL10626642

ZINC: ID ZINC000072179329