BIOPEP-UWM: Report

ID 7541
Name ACE inhibitor from wheat germ hydrolysate
sequence
IVY
Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 393.4760 Monoisotopic mass 393.2256
EC50 :
0.48 µM


Bibliographic data:
Authors
Ueno T., Tanaka M., Matsui T., Matsumoto K.
Title
Determination of antihypertensive small peptides, Val-Tyr and Ile-Val-Tyr, by fluorometric high-performance liquid chromatography combined with a double heart-cut column-swithcing technique. Anal. Sci., 2005, 21, 997-1000
Year Source
2005 Journal


Additional information:
BIOPEP database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccc(cc1)O)C(C)C)[C@H](CC)C

InChI=1S/C20H31N3O5/c1-5-12(4)16(21)18(25)23-17(11(2)3)19(26)22-15(20(27)28)10-13-6-8-14(24)9-7-13/h6-9,11-12,15-17,24H,5,10,21H2,1-4H3,(H,22,26)(H,23,25)(H,27,28)/t12-,15-,16-,17-/m0/s1

InChiKey: QSXSHZIRKTUXNG-STECZYCISA-N


Database reference:
AHTPDB: ID 1579; 1613; 1882; 1886; 2675; 2768; 2858; 3657; 3960; 4762; 5092; 5223; 5517; 5518; 5519; 6189; 6527

BindingDB: ID 50169207

BRENDA: Ligand Ile-Val-Tyr

ChEMBL: ID CHEMBL188747

ChemSpider: ID 9398172

EROP-Moscow: ID E04070

PubChem: ID 11223118