BIOPEP-UWM: Report
| ID | 7546 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
|||
| Chemical mass | 445.5537 | Monoisotopic mass | 445.2681 | |
| EC50 : | 0.21 µM |
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| Bibliographic data: | |
| Authors | |
| Fujita H., Yokoyama K., Yoshikawa M. | |
| Title | |
| Classification of antihypertensive activity of angiotensin I-converting enzyme inhibitory peptides derived from food proteins. J. Food Sci., 65, 564-569, 2000 | |
| Year | Source |
| 2000 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O InChI=1S/C23H35N5O4/c1-3-14(2)20(25)22(30)27-18(10-6-7-11-24)21(29)28-19(23(31)32)12-15-13-26-17-9-5-4-8-16(15)17/h4-5,8-9,13-14,18-20,26H,3,6-7,10-12,24-25H2,1-2H3,(H,27,30)(H,28,29)(H,31,32)/t14-,18-,19-,20-/m0/s1 InChIKey=CEPIAEUVRKGPGP-DSYPUSFNSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001 Peptide obtained also from arachin (Arachis hypogaea) protein hydrolysate; EC50 = 19 um Jimsheena V. K., Gowda L. R., 2010, Arachin derived peptides as selective angiotensin I-converting enzyme (ACE) inhibitors: structure-activity relationship. Peptides, 31, 1165-1176 Peptide released from myosin by simulated gastric juice. Terashima M., Baba T., Ikemoto N., Katayama M., Morimoto T., Matsumura S., 2010, Novel angiotensin-converting enzyme (ACE) inhibitory peptides derived from boneless chicken leg meat. J. Agric. Food Chem., 58, 7432-7436 Activator of Angiotensin 2-converting enzyme (ACE2) (EC 3.4.17.23) (MEROPS ID: M02.006) according to the BIOPEP-UWM database of bioactive peptides |
| Database reference: |
| AHTPDB: ID 1598, 1652, 2021, 2599, 2855, 2859, 2894, 3767, 4202, 4975, 5061, 5718, 6532 BRENDA: Ligand Ile-Lys-Trp ChEBI: ID 158604 ChemSpider: ID 8000528 DFBP: ID DFBPACEI0090; DFBPANHY0514; DFBPMUFU0042 EROP-Moscow: ID E09190 J-Global: ID 200907057574999709 Metabolomics Workbench: ID 82893 Nikkaji: ID J1.356.192C PubChem: CID 9824781 SATPdb: ID satpdb19180 |