BIOPEP-UWM: Report

ID 7565
Name ACE inhibitor
sequence
LHLPLPL
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 802.0128 Monoisotopic mass 801.5097
IC50 :
432.70 µM


Bibliographic data:
Authors
Miguel M., Recio I., Ramos M., Delgado M. A., Aleixandre M. A.
Title
Antihypertensive effect of peptides obtained from Enterococcus faecalis-fermented milk in rats. J. Dairy Sci., 89, 3352-3359, 2006
Year Source
2006 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C[N]([H])C=N1)C(=O)N[C@@H](CC(C)C)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC(C)C)C(=O)N3[C@@H](CCC3)C(=O)N[C@@H](CC(C)C)C(=O)O

InChI=1S/C40H67N9O8/c1-22(2)15-27(41)34(50)44-28(19-26-20-42-21-43-26)35(51)45-29(16-23(3)4)38(54)48-13-9-11-32(48)36(52)46-30(17-24(5)6)39(55)49-14-10-12-33(49)37(53)47-31(40(56)57)18-25(7)8/h20-25,27-33H,9-19,41H2,1-8H3,(H,42,43)(H,44,50)(H,45,51)(H,46,52)(H,47,53)(H,56,57)/t27-,28-,29-,30-,31-,32-,33-/m0/s1

InChIKey=YYTXSZFDTAQSBA-MRNVWEPHSA-N


Hypotensive peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10078); the EROP-Moscow database


Database reference:
AHTPDB: ID 1713, 2493, 2495, 4181, 4344, 5026, 5526, 5821, 6551

BioPepDB: ID biopep00780

BIOPEP-UWM dtabase of bioactive peptides: ID 10078

ChemSpider: ID 9460810

EROP-Moscow: ID E09376

FeptideDB: ID 7565

FermFooDB: ID FMDB1366; FMDB1367; FMDB1502; FMDB1503; FMDB1504; FMDB1505; FMDB1506; FMDB174; FMDB188; FMDB1887

MBPDB: Peptide LHLPLPL

PubChem: CID 11285819

SATPdb: ID satpdb12285