BIOPEP-UWM: Report

ID 7579
Name ACE inhibitor
sequence
GW
Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 261.2759 Monoisotopic mass 261.1110
EC50 :
30.00 µM


Bibliographic data:
Authors
Cheung H.-S., Wang F.-L., Ondetti M. A., Sabo E. F., Cushman D. W.
Title
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J. Biol. Chem., 255, 401-407
Year Source
1980 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C13H15N3O3/c14-6-12(17)16-11(13(18)19)5-8-7-15-10-4-2-1-3-9(8)10/h1-4,7,11,15H,5-6,14H2,(H,16,17)(H,18,19)/t11-/m0/s1

InChIKey=AJHCSUXXECOXOY-NSHDSACASA-N


Inhibitor of Dipeptidyl peptidase IV (DPP IV) (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID: 8787)
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090) according to the BRENDA database; the ChEMBL database
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10472)

Bitter peptide according to the ChEMBL database


Database reference:
AHTPDB: ID 1267, 1418, 1888, 2743, 2846, 3351, 3495, 3785, 3842, 3937, 4446, 4491, 4664, 6207, 6565

BindingDB: ID 50188499

BIOPEP-UWM database of bioactive peptides: ID 8787, 10472

BRENDA: Ligand Gly-Trp

CAS: Registry No 2390-74-1

CHEBI: ID 73921

ChEMBL: ID CHEMBL299759

ChemSpider: ID 83223

DFBP: ID DFBPACEI1228

ECHA: ID 219-235-7

eChemPortal: ID 2390-74-1

EPA CompTox: ID DTXSID301315473

EROP-Moscow: ID E09037

FDA SRS: ID 35BKX0QF16

GSRS: ID 310513ff-0bb3-4266-8034-7c28ae2ca5bb

J-Global: ID 200907021832427001

MeSH: terms Gly-Trp, glycyl-L-tryptophan, glycyltryptophan

Metabolights: ID MTBLC73921

Metabolomics Workbench: ID 78813

Nikkaji: ID J151.152A

NIST Chemistry Webbook: Compound Glycyl-L-tryptophan

PlantPepDB: ID PPepDB_72

PubChem: CID 92181

SATPdb: ID satpdb11189

SureChEMBL: ID SCHEMBL1407979

UNII: ID 35BKX0QF16

ZINC: ID ZINC000001708201