BIOPEP-UWM: Report

ID 7583
Name ACE inhibitor
sequence
AF
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 236.2664 Monoisotopic mass 236.1157
EC50 :
190.00 µM


Bibliographic data:
Authors
Cheung H.-S., Wang F.-L., Ondetti M. A., Sabo E. F., Cushman D. W.
Title
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J. Biol. Chem., 255, 401-407, 1980
Year Source
1980 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C12H16N2O3/c1-8(13)11(15)14-10(12(16)17)7-9-5-3-2-4-6-9/h2-6,8,10H,7,13H2,1H3,(H,14,15)(H,16,17)/t8-,10-/m0/s1

InChIKey=OMNVYXHOSHNURL-WPRPVWTQSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of Tripeptidyl peptidase 2 (EC 3.4.14.10) (MEROPS ID: S08.090 ) according to the BIOPEP-UWM database of bioactive peptides; the BRENDA database; the ChEMBL database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8759)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 50); ChEMBL database; EROP-Moscow database (ID E04069)


Database reference:
AHTPDB: ID 1271; 1363; 1410; 1503; 1678; 1892; 1896; 2591; 2747; 3031; 3222; 3344; 3419; 3465; 3790; 3846; 3886; 4441; 4496; 4679; 5429; 5787; 6211; 6569

BindingDB: ID 50188503

BIOPEP-UWM database of bioactive peptides: ID 8759

BIOPEP-UWM database of sensory peptides and amino acids: ID 50

BRENDA: Ligand Ala-Phe

CAS: Registry No 3061-90-3

ChEBI: ID 73807

ChEMBL: ID CHEMBL57338

ChemIDPlus: ID 3061-90-3

ChemSpider ID: 87414

DFBP: ID DFBPACEI0116;

EPA CompTox: ID DTXSID801312981

EROP-Moscow: ID E04069; E03700

FooDB: ID FDB111753

HMDB: ID HMDB0028694

J-GLOBAL: ID 200907056679638527

MeSH: Terms Ala-Phe; alanylphenylalanine; L-alanyl-L-phenylalanine

Metabolights: ID MTBLC73807

Metabolomics Workbench: ID 78669

Nikkaji: ID J80.627G

NMRShiftDB: ID 60022205

PlantPepDB: ID PPepDB_241

ProbesDrugs: ID PD165131

PubChem: ID 6992394

ZINC: ID ZINC01575524