BIOPEP-UWM: Report

ID 7584
Name ACE inhibitor
sequence
AP
Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 186.2078 Monoisotopic mass 186.1001
EC50 :
230.00 µM


Bibliographic data:
Authors
Cheung H.-S., Wang F.-L., Ondetti M. A., Sabo E. F., Cushman D. W.
Title
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J. Biol. Chem., 255, 401-407, 1980
Year Source
1980 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N1[C@H](C(=O)O)CCC1)C

InChI=1S/C8H14N2O3/c1-5(9)7(11)10-4-2-3-6(10)8(12)13/h5-6H,2-4,9H2,1H3,(H,12,13)/t5-,6-/m0/s1

InChIKey=WPWUFUBLGADILS-WDSKDSINSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 3177); the BRENDA database; the EROP-Moscow database;
Inhibitor of Tripeptidyl peptidase 2 (TPP 2) (EC 3.4.14.10) (MEROPS ID: S08.090) according to the ChEMBL database; the PubChem database; the BRENDA database
Inhibitor of Peptidylprolyl isomerase (EC 5.2.1.8) according to the BRENDA database


Database reference:
AHTPDB: ID 1079, 1118, 1504, 1507, 3223, 3420, 3468, 3554, 3607, 3706, 3792, 3890, 4060, 4438, 4498, 4685, 5135, 5639, 5675, 6162, 6570

BindingDB: ID 50020390

BIOPEP-UWM database of bioactive peptides: ID 3177

BRENDA: Ligand Ala-Pro

CAS: Registry No 13485-59-1

ChEBI: ID 73393

ChEMBL: ID CHEMBL414828

ChemIDplus: ID 013485591

ChemSpider: ID 75359

EChA: ID 236-795-8

EROP-Moscow: ID E09221

FDA SRS: ID C6G5K79L0O

FooDB: ID FDB098189

HMDB: ID HMDB0028695

J-GLOBAL: ID 200907099385554660

MeSH: Terms Ala-Pro; L-alanyl-L-proline

Metabolights: ID MTBLC73393, MTBLC155848

Metabolomics Workbench: ID 78670

Nikkaji: ID J81.627B

NMRShiftDB: ID 60021737

PlantPepDB: ID PPepDB_2898

PubChem: ID 83525

Rhea: ID 155848

SATPdb: ID satpdb17029

SureChEMBL: ID SCHEMBL152403

UNII: ID C6G5K79L0O

Wikidata: ID Q27140485

ZINC: ID ZINC04521128