BIOPEP-UWM: Report

ID 7588
Name ACE inhibitor
sequence
RA

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 245.2781 Monoisotopic mass 245.1484
IC50 :
460.00 µM



Bibliographic data:
Authors
Cushman D. W.
Title
Angiotensin converting enzyme inhibitors:Evolution of a new class of antihypertensive drugs (page 19). in: Horovitz Z. P. (Ed.)(1981), Mechanisms of action and clinical implications, Urban & Schwarzenberg.
Year Source
1981 book



Additional information:
BIOPEP database of bioactive peptides


SMILES: N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)O

InChI=1S/C9H19N5O3/c1-5(8(16)17)14-7(15)6(10)3-2-4-13-9(11)12/h5-6H,2-4,10H2,1H3,(H,14,15)(H,16,17)(H4,11,12,13)/t5-,6-/m0/s1

InChIKey: WVRUNFYJIHNFKD-WDSKDSINSA-N


Peptide activating ubiquitin-mediated proteolysis according to the BIOPEP database of bioactive peptides (ID 4005), the EROP-Moscow database
Peptide inhibiting UBR protein according to the ChEMBL database; the PubChem database
Inhibitor of Leucyltransferase (EC 2.3.2.6) according to the BRENDA database

Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP database of bioactive peptides (ID 8526)
Inhibitor of Bleomycin hydrolase (EC 3.4.22.40) (MEROPS ID: C01.084) according to the BRENDA database

Salty taste enhancing peptide according to the BIOPEP database of sensory peptides and amino acids (ID 420)



Database reference:
AHTPDB: ID 1679; 2999, 3182; 3227; 3531; 3582; 3830; 4018; 4432; 4536; 4678; 6574

BindingDB: ID 50407418

BIOPEP database of bioactive peptides: ID 4005; 8526

BIOPEP database of sensory peptides and amino acids: ID 420

BRENDA: Ligand Arg-Ala

ChEBI: ID 73810

ChEMBL: ID CHEMBL328471

ChemSpider: ID 5383289

PubChem: ID 7020333

SATPdb: ID satpdb10016

ZINC: ID ZINC02562523