BIOPEP-UWM: Report

ID 7590
Name ACE inhibitor
sequence
AA
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 160.1706 Monoisotopic mass 160.0845
IC50 :
620.00 µM


Bibliographic data:
Authors
Cushman D. W.
Title
Angiotensin converting enzyme inhibitors: Evolution of a new class of antihypertensive drugs (page 19). in: Horovitz Z. P. (Ed.)(1981), Mechanisms of action and clinical implications, Urban & Schwarzenberg.
Year Source
1981 book


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C)C(=O)N[C@@H](C)C(=O)O

InChI=1S/C6H12N2O3/c1-3(7)5(9)8-4(2)6(10)11/h3-4H,7H2,1-2H3,(H,8,9)(H,10,11)/t3-,4-/m0/s1

InChIKey: DEFJQIDDEAULHB-IMJSIDKUSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8637); the BRENDA database; the EROP-Moscow database
Inhibitor of Cytosol alanyl aminopeptidase (EC 3.4.11.14) (MEROPS ID: M24.005) according to he the BRENDA database
Inhibitor of D-Ala-D-Ala Dipeptidase (EC 3.4.13.22) (MEROPS ID: M15.011) according to tBRENDA database
Inhibitor of Peptide-transporting ATPase (EC 3.6.3.43) according to the BRENDA database
Activator of Carbonic anhydrases (EC 4.2.1.1) according to the ChEMBL database
Antibacterial peptide according to the ChEMBL database
Hyp[otensive peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10141)

Sweet peptide according to the BIOPEP-UWM database of sensory peptides and amino acids


Database reference:
AHTPDB: ID 1680; 2982; 3229; 3464; 3552; 3608; 3832; 3885; 4431; 4538; 4684; 5134; 6112; 6576

BioPepDB: ID biopep00002

BIOPEP-UWM database of bioactive peptides: ID 8637; 10141

BIOPEP-UWM database of sensory peptides and amino acids: ID 241

BRENDA: Ligand Ala-Ala

ChEBI: ID 72816

ChEMBL: ID CHEMBL17697

ChemIDplus: ID 001948318

ChemSpider: ID 4588478

EPA DSSTox: ID DTXSID00173127

EROP-Moscow: ID E06348

FeptideDB: ID 7590; 8637

FooDB: ID FDB003740

Golm Metabolome Database: ID DF49DD8A-D390-4F75-8C8A-3A07EF07DD48

HMDB: ID HMDB0028680

J-GLOBAL: ID 200907012990949768

KNApSAcK: ID C00017958

MeSH; ID 67002956; term alanylalanine

Metabolomics Workbench: ID 78656

Nikkaji: ID J47.023F

NIST Chemistry WebBook: Compound L-Alanine, N-L-alanyl-

PlantPepDB: ID PPepDB_1

PubChem: CID 6992372

SAPdb: ID 1016

SATPdb: ID satpdb12967

SpectraBase: Compound L-Alanyl-L-alanine

ZINC: ID ZINC01575493