BIOPEP-UWM: Report

ID 7592
Name ACE inhibitor
sequence
FR
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 321.3739 Monoisotopic mass 321.1796
EC50 :
920.00 µM


Bibliographic data:
Authors
Cushman D. W.
Title
Angiotensin converting enzyme inhibitors:Evolution of a new class of antihypertensive drugs (page 19). in: Horovitz Z. P. (Ed.)(1981), Mechanisms of action and clinical implications, Urban & Schwarzenberg.
Year Source
1981 book


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C15H23N5O3/c16-11(9-10-5-2-1-3-6-10)13(21)20-12(14(22)23)7-4-8-19-15(17)18/h1-3,5-6,11-12H,4,7-9,16H2,(H,20,21)(H,22,23)(H4,17,18,19)/t11-,12-/m0/s1

InChIKey=OZILORBBPKKGRI-RYUDHWBXSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) ) according to the BIOPEP-UWM database of bioactive peptides (ID 8780)
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9501); the BRENDA database


Database reference:
ACToR: ID 1238-09-1

AHTPDB: ID 3363; 3481; 3833; 3911; 4429; 4539; 4687; 6578

BindingDB: ID 50407458

BioPepDB: ID biopep00280

BIOPEP-UWM database of bioactive peptides: ID 8780; 9501

BRENDA: Ligand Phe-Arg

ChEBI: ID 73632

ChEMBL: ID CHEMBL291636

ChemSpider: ID 133005

EROP-Moscow: ID E01801

HMDB: ID HMDB0028989

J-GLOBAL: ID 200907017930259977

Metabolights: ID MTBLC73632

Nikkaji: ID J80.106

ParaPep: ID 1268, 1708

PubChem: CID 150903

SATPdb: ID satpdb10396

SureChEMBL: ID SCHEMBL1711701

ZINC: ID ZINC000002384770