BIOPEP-UWM: Report

ID 7593
Name ACE inhibitor
sequence
IF
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 278.3459 Monoisotopic mass 278.1625
EC50 :
930.00 µM


Bibliographic data:
Authors
Cheung H.-S., Wang F.-L., Ondetti M. A., Sabo E. F., Cushman D. W.
Title
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J. Biol. Chem., 255, 401-407, 1980
Year Source
1980 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccccc1)[C@H](CC)C

InChI=1S/C15H22N2O3/c1-3-10(2)13(16)14(18)17-12(15(19)20)9-11-7-5-4-6-8-11/h4-8,10,12-13H,3,9,16H2,1-2H3,(H,17,18)(H,19,20)/t10-,12-,13-/m0/s1

InChIKey: WMDZARSFSMZOQO-DRZSPHRISA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001

Bitter peptide according to the BIOPEP database of sensory peptides and amino acids (ID 53)


Database reference:
AHTPDB: ID 1448; 1897; 2593; 2674; 2978; 3102; 3230; 3332; 3563; 3797; 3948; 4428; 4503; 4700; 5418; 5420; 6579

BindingDB: ID 50407438

BioPepDB: ID biopep00507

BIOPEP-UWM database of sensory peptides and amino acids: ID 53

BRENDA: Ligand Ile-Phe

ChEBI: ID 74075

ChEMBL: ID CHEMBL91330

ChemSpider: ID 5373175

EROP-Moscow: ID E07287

FeptideDB: ID 7593

J-GLOBAL: ID 200907013568908346

Metabolights: ID MTBLC74075

Nikkaji: ID J924.588J

PubChem: CID 7009595

SATPdb: ID satpdb23069

SureChEMBL: ID SCHEMBL3512463

ZINC: ID ZINC000002384816