BIOPEP-UWM: Report

ID 7608
Name ACE inhibitor
sequence
GV
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 174.1971 Monoisotopic mass 174.1001
EC50 :
4600.00 µM


Bibliographic data:
Authors
Cheung H.-S., Wang F.-L., Ondetti M. A., Sabo E. F., Cushman D. W.
Title
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J. Biol. Chem., 255, 401-407
Year Source
1980 Journal


Additional information:

BIOPEP database of bioactive peptides


SMILES: NCC(=O)N[C@@H](C(C)C)C(=O)O

InChI=1S/C7H14N2O3/c1-4(2)6(7(11)12)9-5(10)3-8/h4,6H,3,8H2,1-2H3,(H,9,10)(H,11,12)/t6-/m0/s1

InChIKey: STKYPAFSDFAEPH-LURJTMIESA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001

Inhibitor of Dipeptidyl Peptidase IV (DPPIV) (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP database of bioactive peptides (ID 8786)
Inhibitor of citrulline uptake in yeasts according to ChEMBL database; PubChem database


Bitter peptide according to BIOPEP database of sensory peptides and amino acids (ID 106); ChEMBL database; PubChem database


Database reference:
AHTPDB: ID 1429; 1689; 3021; 3026; 3098; 3119; 3140; 3160; 3241; 3333; 3423; 3811; 3837; 3936; 4412; 4517; 4680; 5435; 6170; 6594

BindingDB: ID 50407462

BIOPEP database of bioactive peptides: ID 8786

BIOPEP database of sensory peptides and amino acids: ID 106

BRENDA: Ligand Gly-Val

ChEBI: ID 73922

ChEMBL: ID CHEMBL56035

ChemSpider: ID 2006926

Crystallography Open Database (COD): ID 2015750

EROP-Moscow: ID E10385

PubChem: ID 2724807

ZINC: ID ZINC01730674