BIOPEP-UWM: Report

ID 7619
Name ACE inhibitor
sequence
LG
Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 188.2236 Monoisotopic mass 188.1157
IC50 :
8800.00 µM


Bibliographic data:
Authors
Cheung H.-S., Wang F.-L., Ondetti M. A., Sabo E. F., Cushman D. W.
Title
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J. Biol. Chem., 255, 401-407
Year Source
1980 Journal


Additional information:
BIOPEP database of bioactive peptides


SMILES: N[C@H](C(=O)NCC(=O)O)CC(C)C

InChI=1S/C8H16N2O3/c1-5(2)3-6(9)8(13)10-4-7(11)12/h5-6H,3-4,9H2,1-2H3,(H,10,13)(H,11,12)/t6-/m0/s1

InChIKey: LESXFEZIFXFIQR-LURJTMIESA-N


Inhibitor of Leucyl aminopeptidase (EC 3.4.11.1) (MEROPS ID: M17.001) according to BRENDA database
Inhibitor of Polar-amino-acid-transporting ATPase (EC 3.6.3.21) according to BRENDA database
Inhibitor of citrulline uptake in yeasts according to ChEMBL database; PubChem database


Bitter peptide according to BIOPEP database of sensory peptides and amino acids; ChEMBL database; PubChem database


Database reference:
AHTPDB: ID 1489; 3045; 3051; 3086; 3132; 3134; 3136; 3251; 3355; 3426; 3515; 3822; 3851; 3977; 4401; 4528; 4654; 5406; 6606

BindingDB: ID 50407456

BIOPEP database of sensory peptides and amino acids: ID 161

BRENDA: Ligand Leu-Gly

ChEBI: ID 74534

ChEMBL: ID CHEMBL55711

ChemIDplus: ID 000686500

ChemSpider: ID 87882

EROP-Moscow: ID E01614

PubChem: ID 97364

ZINC: ID ZINC02164045