BIOPEP-UWM: Report

ID 7622
Name ACE inhibitor
sequence
EG
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 204.1801 Monoisotopic mass 204.0743
EC50 :
10000.00 µM


Bibliographic data:
Authors
Cheung H.-S., Wang F.-L., Ondetti M. A., Sabo E. F., Cushman D. W.
Title
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J. Biol. Chem., 255, 401-407
Year Source
1980 Journal


Additional information:

BIOPEP database of bioactive peptides


SMILES: N[C@H](C(=O)NCC(=O)O)CCC(=O)O

InChI=1S/C7H12N2O5/c8-4(1-2-5(10)11)7(14)9-3-6(12)13/h4H,1-3,8H2,(H,9,14)(H,10,11)(H,12,13)/t4-/m0/s1

InChIKey: LSPKYLAFTPBWIL-BYPYZUCNSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP database of bioactive peptides (ID 8770)
Antagonist of neuroexcitatory amino acids according to the ChEMBL database; the PubChem database

Bitter peptide according to BIOPEP database of sensory peptides and amino acids (ID 232)
Umami peptide according to BIOPEP database of sensory peptides and amino acids (ID 358)


Database reference:
AHTPDB: ID 1487; 3142; 3254; 3335; 3825; 3898; 4398; 4531; 4663; 6609

BindingDB: ID 50188507

BIOPEP database of bioactive peptides: ID 8770

BIOPEP database of sensory peptides and amino acids: ID 232; 358

ChEBI: ID 73505

ChEMBL: ID CHEMBL421361

ChemSpider: ID 4932470

EROP-Moscow: ID E01847

PubChem: ID 6427052

SATpdb: ID satpdb21475

ZINC: ID ZINC01731776