BIOPEP-UWM: Report

ID 7622
Name ACE inhibitor
sequence
EG

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 204.1801 Monoisotopic mass 204.0743
IC50 :
10000.00 µM



Bibliographic data:
Authors
Cheung H.-S., Wang F.-L., Ondetti M. A., Sabo E. F., Cushman D. W.
Title
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J. Biol. Chem., 255, 401-407, 1980
Year Source
1980 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)NCC(=O)O)CCC(=O)O

InChI=1S/C7H12N2O5/c8-4(1-2-5(10)11)7(14)9-3-6(12)13/h4H,1-3,8H2,(H,9,14)(H,10,11)(H,12,13)/t4-/m0/s1

InChIKey=LSPKYLAFTPBWIL-BYPYZUCNSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8770)
Antagonist of neuroexcitatory amino acids according to the ChEMBL database; the PubChem database

Bitter peptide according to BIOPEP-UWM database of sensory peptides and amino acids (ID 232)
Umami peptide according to BIOPEP-UWM database of sensory peptides and amino acids (ID 358)



Database reference:
AHTPDB: ID 1487; 3142; 3254; 3335; 3825; 3898; 4398; 4531; 4663; 6609

BindingDB: ID 50188507

BIOPEP-UWM database of bioactive peptides: ID 8770

BIOPEP-UWM database of sensory peptides and amino acids: ID 232; 358

ChEBI: ID 73505

ChEMBL: ID CHEMBL421361

ChemSpider: ID 4932470

DFBP: ID DFBPACEI1627

EROP-Moscow: ID E01847

PubChem: ID 6427052

SATpdb: ID satpdb21475

ZINC: ID ZINC01731776