BIOPEP-UWM: Report

ID 7658
Name ACE inhibitor from alphas2-CN (174-181)
sequence
FALPQYLK
Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001).
 
Number of residues
8
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 979.1693 Monoisotopic mass 978.5521
IC50 :
4.30 µM


Bibliographic data:
Authors
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
Title
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315, 2006
Year Source
2006 book


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C49H74N10O11/c1-28(2)24-37(45(65)55-36(49(69)70)14-9-10-22-50)56-46(66)38(27-32-16-18-33(60)19-17-32)57-44(64)35(20-21-41(52)61)54-47(67)40-15-11-23-59(40)48(68)39(25-29(3)4)58-42(62)30(5)53-43(63)34(51)26-31-12-7-6-8-13-31/h6-8,12-13,16-19,28-30,34-40,60H,9-11,14-15,20-27,50-51H2,1-5H3,(H2,52,61)(H,53,63)(H,54,67)(H,55,65)(H,56,66)(H,57,64)(H,58,62)(H,69,70)/t30-,34-,35-,36-,37-,38-,39-,40-/m0/s1

InChIKey=AIBFLFDJKNLEHK-FTSPKJONSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8151); the DFBP database

Bitter peptide according to the BIOPEP database of sensory peptides and amino acids (ID 387); the EROP-Moscow database

Predicted antithrombotic peptide according to the BIOPEP-UWM Virtual database (ID 215)


Database reference:
AHTPDB: ID 2333, 5555, 5841, 6377

BIOPEP-UWM database of bioactive peptides: ID 8151

BIOPEP-UWM database of sensory peptides and amino acids: ID 387

BIOPEP-UWM Virtual database: ID 215

ChemSpider: ID 8571604

DFBP: ID DFBPACEI1679; DFBPACEI1726; DFBPANOX0714; DFBPMUFU0483; DFBPANTH0159

EROP Moscow: ID E03683

FeptideDB: ID 7658; 8151

PubChem: CID 10396165

SATPdb: ID satpdb22987