BIOPEP-UWM: Report

ID 7678
Name ACE inhibitor from dried bonito
sequence
LKPNM

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 601.7583 Monoisotopic mass 601.3247
EC50 :
2.40 µM



Bibliographic data:
Authors
Yokoyama K., Chiba H., Yoshikawa M.
Title
Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito. Biosci. Biotech. Biochem., 56, 1541-1545, 1992
Year Source
1992 Journal



Additional information:
BIOPEP database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C26H47N7O7S/c1-15(2)13-16(28)22(35)30-17(7-4-5-10-27)25(38)33-11-6-8-20(33)24(37)32-19(14-21(29)34)23(36)31-18(26(39)40)9-12-41-3/h15-20H,4-14,27-28H2,1-3H3,(H2,29,34)(H,30,35)(H,31,36)(H,32,37)(H,39,40)/t16-,17-,18-,19-,20-/m0/s1

InChIKey: UHUTUNQDWZAIEF-HVTWWXFQSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001



Database reference:
AHTPDB: ID 1022, 1068, 1072, 1659, 1952, 2024, 2944, 3769, 4221, 5006, 5328, a5512, 5560, 5660

BRENDA: Ligand Leu-Lys-Pro-Asn-Met

ChemSpider: ID 8049201

EROP-Moscow: ID E01437

J-GLOBAL: ID 200907042194666890

Nikkaji: ID J1.356.199K

PepBank: Peptide LKPNM

PubChem: CID 9873512

SATPdb: ID satpdb27562