BIOPEP-UWM: Report

ID 7681
Name ACE inhibitor from soy
sequence
DG
Function:
Inhibitor of Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 190.1536 Monoisotopic mass 190.0587
IC50 :
12.30 µM


Bibliographic data:
Authors
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
Title
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
Year Source
2006 book


Additional information:
BIOPEP database of bioactive peptides


SMILES: N[C@@H](CC(=O)O)C(=O)NCC(=O)O

InChI=1S/C6H10N2O5/c7-3(1-4(9)10)6(13)8-2-5(11)12/h3H,1-2,7H2,(H,8,13)(H,9,10)(H,11,12)/t3-/m0/s1

InChIKey: JHFNSBBHKSZXKB-VKHMYHEASA-N


Another reference concerning ACE inhibition:
Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713


Umami peptide according to the BIOPEP database of sensory peptides and amino acids; EROP-Moscow database (ID 351)
Bitter peptide according to the BIOPEP database of sensory peptides and amino acids (ID 352)


Database reference:
AHTPDB: ID 1042; 1265; 1404; 1492; 1694; 1830; 2911; 3161; 3189; 3263; 3317; 3471; 3826; 3896; 4396; 4532; 4666; 5141; 6224; 6667

BindingDB: ID 50188502

BIOPEP database of sensory peptides and amino acids: ID 351; 352

BRENDA: Ligand Asp-Gly

ChEBI: ID 73450

ChEMBL: ID CHEMBL421171

ChemIDplus: ID 003790510

ChemSpider: ID 133220

EROP-Moscow: ID E01843

PubChem: ID 151148

SATPdb: ID satpdb12356

ZINC: ID ZINC02384840