BIOPEP-UWM: Report

ID 7741
Name ACE inhibitor
sequence
RR
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 330.3856 Monoisotopic mass 330.2123
IC50 :
267.10 µM


Bibliographic data:
Authors
Sentandreu M. A., Toldra F.
Title
Evaluation of ACE inhibitory activity of dipeptides generated by the action of porcine muscle dipeptidyl peptidases. Food Chem., 101, 1629-1633, 2007
Year Source
2007 Journal


Additional information:

BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C12H26N8O3/c13-7(3-1-5-18-11(14)15)9(21)20-8(10(22)23)4-2-6-19-12(16)17/h7-8H,1-6,13H2,(H,20,21)(H,22,23)(H4,14,15,18)(H4,16,17,19)/t7-,8-/m0/s1

InChIKey=OMLWNBVRVJYMBQ-YUMQZZPRSA-N

Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP-UWM database of bioactive peptides (ID 8889)
Inhibitor of Leucyltransferase (EC 2.3.2.6) according to BRENDA database
Inhibitor of HIV-1 retropepsin (EC 3.4.23.16) (MEROPS ID: A02.001) according to BRENDA database
Antinociceptive peptide according to ChEMBL database
Inhibitor of Dipeptidyl peptidase III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.003) according to the BIOPEP-UWM database of bioactive peptides (ID:9485)
Antibacterial peptide according to the ChEMBL database
Hemolytic peptide according to the ChEMBL database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 2)

Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
ACToR: ID 15483-27-9

AHTPDB: ID 3273; 3534; 4023; 4738; 5170; 5432; 6108; 6689

BindingDB: ID 50188488

BioPepDB: ID biopep01222

BIOPEP-UWM database of bioactive peptides: ID 8889; 9485

BIOPEP-UWM database of sensory peptides and amino acids: ID 2

BRENDA: Ligand Arg-Arg

ChEBI: ID CHEBI:73811

ChEMBL: ID CHEMBL296756

ChemIDplus: ID 15483-27-9

ChemSpider: ID 133932

CTD: ID 15483-27-9

eChemPortal: ID 15483-27-9

EPA CompTox: ID DTXSID60165745

EPA DSSTox: ID DTXCID2088236

EROP-Moscow: ID E14727

HMDB: ID HMDB0028703

J-GLOBAL: ID 200907087384149330

Metabolights: ID MTBLC73811

Nikkaji: ID J531.298A

PubChem: CID 151956

SATPdb: ID satpdb21704

SureChEMBL: ID SCHEMBL288599

ZINC: ID ZINC000005706877