BIOPEP-UWM: Report

ID 7752
Name ACE inhibitor from shark meat hydrolysate
sequence
EY

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 310.3018 Monoisotopic mass 310.1160
EC50 :
2.68 µM



Bibliographic data:
Authors
Wu H., He H-L, Chen X-L, Sun C-Y, Zhang Y-Z, Zhou B-C.
Title
Purification and identification of novel angiotensin I-converting enzyme inhibitory peptides from shark meat hydrolysate. Process Biochemistry, 43, 457-461, 2008
Year Source
2008 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCC(=O)O)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C14H18N2O6/c15-10(5-6-12(18)19)13(20)16-11(14(21)22)7-8-1-3-9(17)4-2-8/h1-4,10-11,17H,5-7,15H2,(H,16,20)(H,18,19)(H,21,22)/t10-,11-/m0/s1

InChIKey: YSWHPLCDIMUKFE-QWRGUYRKSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.acBIOPEP-UWM database of bioactive peptides.uk/); ID: M02-001


Inhibitor of Tubulin-tyrosine ligase (EC 6.3.2.25) according to the BIOPEP-UWM database of bioactive peptides, the BRENDA database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides

Bitter peptide according to the BIOPEP database of sensory peptides and amino acids (ID 273)
Umami peptide according to the BIOPEP database of sensory peptides and amino acids (ID 413)




Database reference:
AHTPDB: ID 1115; 2819; 3276; 3322; 3477; 3903; 4722; 5145; 6193; 6700

BIOPEP-UWM database of bioactive peptides: ID 8777

BIOPEP-UWM database of sensory peptides and amino acids: ID 273; 413

BRENDA: Ligand Glu-Tyr

ChEBI: ID 73513

ChemSpider: ID 449883

PubChem: ID 515717

SATPdb: ID satpdb17435

ZINC: ID ZINC01605476