BIOPEP-UWM: Report

ID 7801
Name ACE inhibitor
sequence
VRYL
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 549.6612 Monoisotopic mass 549.3265
IC50 :
24.10 µM


Bibliographic data:
Authors
Gómez Ruiz J. Á., Ramos M., Recio I.
Title
Angiotensin converting enzyme-inhibitory activity of peptides isolated from Manchego cheese. Stability under simulated gastrointestinal digestion. Int. Dairy J., 14, 1075-1080, 2004
Year Source
2004 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C26H43N7O6/c1-14(2)12-20(25(38)39)33-23(36)19(13-16-7-9-17(34)10-8-16)32-22(35)18(6-5-11-30-26(28)29)31-24(37)21(27)15(3)4/h7-10,14-15,18-21,34H,5-6,11-13,27H2,1-4H3,(H,31,37)(H,32,35)(H,33,36)(H,38,39)(H4,28,29,30)/t18-,19-,20-,21-/m0/s1

InChIKey=BYUOUPCTZUCTKM-TUFLPTIASA-N


Database reference:
AHTPDB: ID 1338, 3622, 4317, 5707, 6702

CAS: Registry No 628318-36-5

EPA CompTox: ID DTXSID00796537

MBPDB: Peptide VRYL

Nikkaji: ID J2.108.786F

PubChem: CID 71373723

SATPdb: ID satpdb11696

SureChEMBL: ID 30954448

UniChem: ID 42135432

Wikidata: ID Q82767404