BIOPEP-UWM: Report

ID 7810
Name ACE inhibitor from anchovy and bonito
sequence
KP
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 243.3019 Monoisotopic mass 243.1578
EC50 :
22.00 µM


Bibliographic data:
Authors
Ichimura T., Hu J., Aita D. Q., Maruyama S.
Title
Angiotensin I-converting enzyme inhibitory activity and insulin secretion stimulative activity of fermented fish sauce. J. Biosci. Bioeng., 96, 496-499, 2003
Year Source
2003 Journal


Additional information:
BIOPEP database of bioactive peptides


SMILES: C1C[C@H](N(C1)C(=O)[C@H](CCCCN)N)C(=O)O

InChI=1S/C11H21N3O3/c12-6-2-1-4-8(13)10(15)14-7-3-5-9(14)11(16)17/h8-9H,1-7,12-13H2,(H,16,17)/t8-,9-/m0/s1

InChIKey: AIXUQKMMBQJZCU-IUCAKERBSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001


Antioxidative peptide according to BIOPEP database of bioactive peptides (ID 8218)
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP database of bioactive peptides (ID 8519)

Bitter peptide according to BIOPEP database of sensory peptides and amino acids


Peptide found in fish sauce.

Ichimura T., Hu J., Aita D. Q., Maruyama S., 2003, Angiotensin I-converting enzyme inhibitory activity and insulin secretion stimulative activity of fermented fish sauce. J. Biosci. Bioeng., 96, 496-499

Peptide found in chicken egg protein hydrolysate.

Huang W.-Y., Majumder K., Wu J., 2010, Oxygen radical absorbance capacity of peptides from egg white protein ovotransferrin and their interactions with phytochemicals. Food Chem., 123, 635-641


Database reference:
AHTPDB: ID 1119; 1435; 1471; 1514; 3015; 3037; 3130; 3155; 3277; 3339; 3510; 3568; 3751; 3969; 4705; 5159; 5453; 5640; 6713

BIOPEP database of bioactive peptides: ID 8218; 8519

BIOPEP database of sensory peptides and amino acids: ID 14

BRENDA: Ligand Lys-Pro

ChEBI: ID 74567

ChemSpider: ID 149672

EROP-Moscow: ID E10446

PubChem: ID 171204

ZINC: ID ZINC03791059