BIOPEP-UWM: Report

ID 7821
Name Rapakinin - ACE inhibitor
sequence
RIY

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 450.5305 Monoisotopic mass 450.2583
IC50 :
28.00 µM



Bibliographic data:
Authors
Marczak E. D., Usui H., Fujita H., Yang Y., Yokoo M., Lipkowski A. W., Yoshikawa M.
Title
New antihypertensive peptides isolated from rapeseed. Peptides, 24, 791-798, 2006
Year Source
2006 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CCCNC(=N)N)C(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C21H34N6O5/c1-3-12(2)17(27-18(29)15(22)5-4-10-25-21(23)24)19(30)26-16(20(31)32)11-13-6-8-14(28)9-7-13/h6-9,12,15-17,28H,3-5,10-11,22H2,1-2H3,(H,26,30)(H,27,29)(H,31,32)(H4,23,24,25)/t12-,15-,16-,17-/m0/s1

InChIKey=FNXCAFKDGBROCU-STECZYCISA-N


Appetite regulating (anorexigenic) peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10135)
Hypotensive peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10134)
Opioid antagonist according to the BIOPEP-UWM database of bioactive peptides (ID 10133)





Database reference:
AHTPDB: ID 1569, 1949, 2957, 4247, 4754, 4982, 5114, 5247, 6142, 6724

BIOPEP-UWM database of bioactive peptides: ID 10133; 10134; 10135

ChEBI: ID 159074

ChemSpider: ID 8000749

EPA DSSTox: ID DTXSID50431365

EROP-Moscow: ID E05001

FeptideDB: ID 7821

J-GLOBAL: ID 200907091912921056

MeSH: term arginyl-isoleucyl-tyrosine; ID C514605

Nikkaji: ID J1.911.456B

PubChem: CID 9825002

SATPdb: ID satpdb16973