BIOPEP-UWM: Report

ID 7835
Name ACE inhibitor
sequence
AH
Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 226.2319 Monoisotopic mass 226.1063
IC50 :
9000.00 µM


Bibliographic data:
Authors
van Platerink C. J., Janssen H.-G. M., Haverkamp J.
Title
Application of at-line two-dimensional liquid chromatography-mass spectrometry for identification of small hydrophilic angiotensin I-inhibiting peptides in milk hydrolysates. Anal. Bioanal. Chem., 2008, 391, 299-307.
Year Source
2008 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C)C(=O)N[C@@H](CC1=C[N]([H])C=N1)C(=O)O

InChI=1S/C9H14N4O3/c1-5(10)8(14)13-7(9(15)16)2-6-3-11-4-12-6/h3-5,7H,2,10H2,1H3,(H,11,12)(H,13,14)(H,15,16)/t5-,7-/m0/s1

InChIKey=XZWXFWBHYRFLEF-FSPLSTOPSA-N


IC50 according to:
Wang Z., Zhang S., Jin H., Wang W., Huo J., Zhou L., Wang Y., Feng F., Zhang L., 2011, Angiotensin-I-converting enzyme inhibitory peptides: Chemical feature based pharmacophore generation. Eur. J. Med. Chem., 46, 3428-3433


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the the BIOPEP-UWM database of bioactive peptides (ID 8761)
Antioxidative peptide according to the the BIOPEP-UWM database of bioactive peptides (ID 7886); the EROP-Moscow database

Umami peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 522)
Sour peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 523)


Database reference:
AHTPDB: ID 1253, 3288, 3326, 3467, 3888, 6738

BindingDB: ID 50348857

BIOPEP-UWM database of bioactive peptides: ID 7886; 8761

BIOPEP-UWM database of sensory peptides and amino acids: ID 522; 523

BRENDA: Ligand Ala-His

ChEBI: ID 73771

ChEMBL: ID CHEMBL1221620

ChemSpider: ID 8013175

EChA: ID 3253-17-6

EPA DSSTox: ID DTXCID101474629

EROP-Moscow: ID E09133

FeptideDB: ID 7835; 7886; 8761

HMDB: ID HMDB0028689

J-GLOBAL: ID 200907012902688798

MeSH: term alanylhistidine; ID C061116

Metabolights: ID MTBLC73771

MetaCyc: ID CPD-13401

Nikkaji: ID J899K

PubChem: CID 9837455

SATPdb: ID satpdb24875

Seed: ID cpd11584

ZINC: ID ZINC000005115824