BIOPEP-UWM: Report
| ID | 7853 |
| Name | Anticancer peptide Met-enkephalin |
| sequence |
| Function: | |||
| Anticancer | |||
| Number of residues | 5 |
Activity code | ac |
| Activity : | anticancer |
|||
| Chemical mass | 573.6608 | Monoisotopic mass | 573.2249 | |
| EC50 : | 0.00 µM |
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| Bibliographic data: | |
| Authors | |
| Horvat S, Mlinarić-Majerski K, Glavas-Obrovac L, Jakas A, Veljković J, Marczi S, Kragol G, Roscić M, Matković M, Milostić-Srb A. | |
| Title | |
| Tumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity. J. Med. Chem., 49, 3136-3142, 2006 | |
| Year | Source |
| 2006 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCSC)C(O)=O InChI=1S/C27H35N5O7S/c1-40-12-11-21(27(38)39)32-26(37)22(14-17-5-3-2-4-6-17)31-24(35)16-29-23(34)15-30-25(36)20(28)13-18-7-9-19(33)10-8-18/h2-10,20-22,33H,11-16,28H2,1H3,(H,29,34)(H,30,36)(H,31,35)(H,32,37)(H,38,39)/t20-,21-,22-/m0/s1 InChIKey=YFGBQHOOROIVKG-FKBYEOEOSA-N Opioid peptide according to the BindingDB database, the BIOPEP-UWM database of bioactive peptides (ID 2877), the ChEMBL database; the EROP-Moscow database, the PepBank database, the PubChem database Antioxidative peptide according to the BIOEP-UWM database of bioactive peptides (ID 8123) Inhibitor of Tripeptide aminopeptidase (EC 3.4.11.4) (MEROPS ID: M20.003) according to the BRENDA database Inhibitor of Aminopeptidase A (EC 3.4.11.7) (MEROPS ID: M01.003) according to the BRENDA database Inhibitor of Dipeptidyl peptidase III (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9522); the BRENDA database Inhibitor of Carboxypeptidase E (EC 3.4.17.10) (MEROPS ID: M14.005) according to the BRENDA database Inhibitor of Neprilysin (EC 3.4.24.1) (MEROPS ID: M13.001) according to the BRENDA database Inhibitor of Dactylysin (EC 3.4.24.60) (MEROPS ID: M9G.026) according to the BRENDA database Inhibitor of Neprilysin-2 (EC 3.4.24.B14) (MEROPS ID: M13.008) according to the BRENDA database |
| Database reference: |
| BindingDB: ID 50019056 BIOPEP-UWM database of bioactive peptides: ID 2877; 8123; 9522 BRAINPEPS: ID 29 BRENDA: Ligand MET-enkephalin ChEBI: ID 6618 ChEMBL: ID CHEMBL13786 ChemDB: ID 000187 ChemSpider: ID 391597 DrugBank: ID DB12668 EPA CompTox: ID DTXSID80332078 EPA DSSTox: ID DTXCID80283172 EROP-Moscow: ID E00145 FDA SRS: ID 9JEZ9OD3AS HMRBase: ID hmrbase_10314; hmrbase_10378; hmrbase_10385; hmrbase_11282; hmrbase_11501 IUPHAR/BPS: ID 1614 J-GLOBAL: ID 200907066709437829 KEGG: ID C11684 MMDB: ID 26823.1 NeuroPep: ID NP04067; NP04095; NP04114; NP04122; NP04132; NP04143; NP04159; NP04178; NP04198; NP04723; NP04731; NP04748; NP04761; NP04771; NP04779; NP04790; NP04798; NP04805; NP04814; NP04837; NP04847; NP04859; NP04867 Nikkaji: ID J246.108K PepBank: Peptide YGGFM PEPLife: ID 2892; 2902 PeptideDB: ID PEP02836; PEP02846; PEP02856; PEP02866; PEP02876; PEP02886; PEP02903; PEP02907; PEP02909; PEP02916; PEP02922; PEP02926; PEP03466; PEP03600; PEP03610; PEP03684; PEP04183; PEP04321; PEP04352; PEP04863; PEP05014; PEP05061; PEP05108; PEP06089; PEP06218; PEP08590; PEP08693; PEP08702; PEP10161; PEP12157; PEP12974; PEP15526; PEP17263; PEP17531; PEP19959; PEP19968; PEP19976 PubChem: CID 443363 SATPdb: ID satpdb26280 SureChEMBL: ID SCHEMBL632433 ZINC: ID ZINC000004102171 |